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IL1A — PARP1

Text-mined interactions from Literome

Huang et al., Biochem Biophys Res Commun 2009 (Disease Models, Animal...) : Minocycline repressed the expression of TNF-alpha, IL-1beta , and iNOS, decreased the apoptotic index, and inhibited poly(ADP-ribose) polymerase-1 ( PARP-1 ) activity in the mouse small intestine
Rolli et al., Crit Care 2010 (Systemic Inflammatory Response Syndrome) : Plasma TNFa, IL-6 and MIP-2 disclosed a transient peak, whereas IL-1ß and soluble TREM-1 steadily increased over 6 h. Flagellin also triggered a marked cleavage of caspase-3 and PARP in the intestine, pointing to its ability to promote significant apoptosis in this organ