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CSK — MAPK1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: MAPK1 → CSK (decreases, CSK Activity, MAPK1 Activity) Liu et al., J Leukoc Biol 2001*
  Evidence: Transfection of the native Src inhibitor, C-terminal Src kinase (Csk), also suppressed crystal-induced c-Src, ERK1/2, and IkappaBalpha phosphorylation and IL-8 expression.

Text-mined interactions from Literome

Zagozdzon et al., Cell Signal 2006 (MAP Kinase Signaling System) : In this work, we compared the effect of CHK versus Csk on MAPK signaling and elucidated the signaling pathway mediated by CHK leading to the activation of Erk1/2 ... Exogenous expression of wild-type CHK, but not Csk or a dead-kinase mutant of CHK, resulted in enhanced Erk1/2 phosphorylation in PC12 cells
Choudhury et al., Cell Signal 2006 : Inhibition of c-Src tyrosine kinase blocked PDGF stimulated MAPK activity and resulted in attenuation of c-fos gene transcription with concomitant prevention of Elk-1 transactivation
Beaulieu et al., Blood 2011 : Using Meg-01 cells and mouse megakaryocytes, we found that NF?B, ERK-MAPK , and PI3K/Akt pathways, known downstream pathways of TLRs, are activated by Pam3CSK4 , a TLR2-specific ligand