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PYY — SCT
Text-mined interactions from Literome
Lluis et al., Biol Signals 1992
:
The purpose of this study was to characterize the effect of peptide YY (PYY) on acid stimulated pancreatic bicarbonate secretion and to determine whether
PYY affects the release of
secretin in response to intraduodenal infusion of acid
Raufman et al., Am J Physiol 1991
:
PYY and NPY, but not pancreatic polypeptide, starting at nanomolar concentrations,
caused a 40-50 % inhibition of
secretin- , vasoactive intestinal polypeptide-, prostaglandin E2-, and forskolin induced increases in chief cell adenosine 3',5'-cyclic monophosphate ( cAMP ) content and pepsinogen secretion
Guo et al., Gastroenterology 1987
:
Furthermore,
PYY had no significant effect on either the basal release of
secretin , gastric inhibitory polypeptide, pancreatic polypeptide, or neurotensin, or on the stimulated release of pancreatic polypeptide by 2-deoxyglucose
Tatemoto et al., Proc Natl Acad Sci U S A 1982
:
PYY has been found to strongly
inhibit both
secretin- and cholecystokinin stimulated pancreatic secretion in the anesthetized cat
Guan et al., Regul Pept 1993
:
This study was undertaken therefore to determine the role of endogenous CCK and the
effects of exogenous caerulein,
secretin and bombesin on
PYY release ... These results suggest the involvement of endogenous CCK in PYY release but this mediation seems to necessitate the participation of other as yet unknown factors since exogenous caerulein,
secretin or bombesin can not
induce PYY release when given alone
Teyssen et al., Pancreas 1996
:
PYY 1-36 and the Y2 receptor agonist PYY 3-36 significantly inhibited pancreatic secretory
responses to
secretin and cerulein, whereas inhibition by NPY 1-36 and the Y2 receptor agonist PYY 13-36 was attainable only at doses of 1,000 and 2,000 pmol/kg/h