Gene interactions and pathways from curated databases and text-mining

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SGK1 — SLC12A3

Text-mined interactions from Literome

Vallon et al., American journal of physiology. Renal physiology 2009 (Hyperkalemia) : Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1
Lang et al., Curr Opin Nephrol Hypertens 2009 (Hypertension...) : SGK1 is essential for optimal processing of the epithelial sodium channel and also regulates the expression of the Na+-Cl- cotransporter
Arroyo et al., J Am Soc Nephrol 2011 : Taken together, these results suggest that aldosterone modulates NCC protein expression via a pathway involving SGK1 and Nedd4-2 and provides an explanation for the well-known aldosterone induced increase in NCC protein expression