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CDC42 — GRAP2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Philips et al., J Biol Chem 2000
:
Differential
effect of Rac and
Cdc42 on
p38 kinase activity and cell cycle progression of nonadherent primary mouse fibroblasts
Lamalice et al., Oncogene 2004
:
Moreover, the expression of a dominant negative form of
Cdc42 ( Cdc42 N17 )
inhibited the activation of
SAPK2/p38 and of its direct target MAP kinase activated protein kinase 2
Fessler et al., J Biol Chem 2004
:
Methyl-beta-cyclodextrin induces activation of p38 and
Cdc42 , but not Rac, in the nonstimulated PMN, yet
inhibits subsequent lipopolysaccharide induced activation of
p38 and Cdc42
Chan et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Overexpression of a PAK inhibitory peptide or dominant negative Cdc42 revealed that
p38 activation was
dependent on PAK and
Cdc42 activities
Gamell et al., PloS one 2011
:
These signaling effects on
p38/MK2/Hsp25 do not
require the activity of either
Cdc42 or PAK, whereas p38/MK2 activities do not significantly modify the BMP-2 dependent activation of LIMK1, measured by either kinase activity or with an antibody raised against phospho-threonine 508 at its activation loop