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BNIP2 — RHOA
Text-mined interactions from Literome
Zhou et al., Oncogene 2006
:
These overlapping motifs allow tripartite competition such that overexpression of
BNIP-Salpha could reduce p50RhoGAP binding to RhoA and
restore RhoA activation ... Therefore, via unique binding motifs within its BCH domain,
BNIP-Salpha could interact and
activate RhoA while preventing its inhibition by p50RhoGAP
Soh et al., J Cell Sci 2008
(Cell Transformation, Neoplastic) :
BNIP2 extra long
inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain