Gene interactions and pathways from curated databases and text-mining

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BNIP2 — RHOA

Text-mined interactions from Literome

Zhou et al., Oncogene 2006 : These overlapping motifs allow tripartite competition such that overexpression of BNIP-Salpha could reduce p50RhoGAP binding to RhoA and restore RhoA activation ... Therefore, via unique binding motifs within its BCH domain, BNIP-Salpha could interact and activate RhoA while preventing its inhibition by p50RhoGAP
Soh et al., J Cell Sci 2008 (Cell Transformation, Neoplastic) : BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain