Li et al., J Biol Chem 2002
(Carcinoma...) :
Mutations within a 70-base pair domain that includes binding sites for NKX2.1, hepatocyte nuclear factor 3 ( HNF-3 ), or cAMP response element binding protein ( CREB ) eliminated SMAD3 dependent repression of Sp-B transcription
Minoo et al., Nucleic Acids Res 2008
:
SMAD3 prevents binding of NKX2.1 and FOXA1 to the SpB promoter through its MH1 and MH2 domains