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PTEN — TCF20

Text-mined interactions from Literome

Persad et al., J Cell Biol 2001 : TCF promoter/luciferase reporter assays and gel mobility shift analysis demonstrate that PTEN also suppresses TCF transcriptional activity
Virolle et al., Nat Cell Biol 2001 (Neoplasms) : The Egr-1 transcription factor directly activates PTEN during irradiation induced signalling
Jomary et al., Invest Ophthalmol Vis Sci 2006 (Retinal Degeneration) : In the period up to the peak of photoreceptor apoptosis at postnatal day 15, dysregulation of the survival pathway was identified at several levels, including deactivation of both Akt itself and its downstream transcription factor target Forkhead ( FKHR ) and activation of the upstream negative regulator PTEN
Teresi et al., Hum Mol Genet 2008 : We, therefore, studied the full-length PTEN promoter through serial deletion reporter assays and electromobility shift assays and identified a region between -854 and -791 that binds an as-yet unidentified transcription factor , through which the statins induce PTEN expression
Choi et al., Glycobiology 2008 (Colonic Neoplasms) : The AP-2alpha transcription factor is required for the ganglioside GM3 stimulated transcriptional regulation of a PTEN gene ... These results suggest that the AP-2alpha transcription factor is required for the ganglioside GM3 stimulated transcriptional regulation of the PTEN gene
Yu et al., EMBO J 2009 : The PTEN tumour suppressor gene is induced by the early growth response 1 (EGR1) transcription factor , which also transactivates p53, p73, and p300/CBP as well as other proapoptotic and anti-cancer genes
Wu et al., Neoplasia (New York, N.Y.) 2009 (Genetic Predisposition to Disease...) : Computational and promoter-reporter evaluations implicated the E2F transcription factor in PTEN regulation of cdc6 and cyclin E2 expression