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MAPK12 — PRX
Text-mined interactions from Literome
Hess et al., J Biol Chem 2003
:
The p38
MAPK inhibitor SB202190 and overexpression of dominant negative mutants of MAPK kinase 4 ( MKK4 ), MKK6, and p38
inhibited the TPA dependent induction of
Prx I gene transcription
Conway et al., J Biol Chem 2006
:
Additionally, our data show that activation of p38
MAPK in oxLDL treated macrophages was
dependent on the up-regulation of
Prx I. Reduction of Prx I expression by small interfering RNA transfection resulted in a significant decrease in p38 MAPK activation, whereas the up-regulation of Prx I expression with either oxLDL or ethoxyquin led to increased p38 MAPK activation