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CDC20 — FZR1

Pathways - manually collected, often from reviews:

• KEGG Cell cycle: Complex of 14 proteins → Complex of 14 proteins (protein-protein, activation)
• Reactome Reaction: CDC20 → FZR1 (reaction)
• Reactome Reaction: CDC20 → FZR1 (indirect_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDC20 — FZR1 (physical association, affinity chromatography technology) Stewart et al., Mol Cell Biol 2005*
• IRef Biogrid Interaction: CDC20 — FZR1 (physical association, affinity chromatography technology) Wang et al., J Biol Chem 2007*
• IRef Biogrid Interaction: CDC20 — FZR1 (direct interaction, enzymatic study) Tian et al., Proc Natl Acad Sci U S A 2012*
• IRef Biogrid Interaction: CDC20 — FZR1 (direct interaction, pull down) Hyun et al., Biochem Biophys Res Commun 2013*
• IRef Biogrid Interaction: CDC20 — FZR1 (physical association, affinity chromatography technology) Hyun et al., Biochem Biophys Res Commun 2013*
• Gene Ontology Complexes anaphase-promoting complex: anaphase-promoting complex complex (MAD2L2-ANAPC2-CDC23-ANAPC15-CDC26-UBE2C-ANAPC16-ANAPC11-ANAPC13-CDC20-FZR1-ANAPC1-CUL7-ANAPC4-ANAPC7) Gmachl et al., Proc Natl Acad Sci U S A 2000, Pfleger et al., Genes Dev 2001, Dias et al., Proc Natl Acad Sci U S A 2002, Kraft et al., EMBO J 2003, Dube et al., Mol Cell 2005, Jin et al., Cell 2008, Williamson et al., Proc Natl Acad Sci U S A 2009, Mansfeld et al., Nat Cell Biol 2011, Zhao et al., Genomics 1998
• IRef Hprd Interaction: Complex of 17 proteins (in vivo) Kramer et al., Curr Biol 1998*
• IRef Intact Interaction: Complex of 18 proteins (association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 22 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of FZR1-AURKA-CDC23-ANAPC1-ANAPC4-CDC27-CDC16-CDC20 (association, anti tag coimmunoprecipitation) Kim et al., Cancer Cell 2011
• IRef Intact Interaction: Complex of 21 proteins (association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 23 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 19 proteins (association, tandem affinity purification) Hutchins et al., Science 2010