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ACP1 — PTH
Text-mined interactions from Literome
Mohan et al., Bone 2000
:
PTH ( 1-34 )
caused significant increases in serum calcium ( after 4 h ) and tartrate-resistant
acid phosphatase activity in bone extract ( after 4 h ), whereas PTH ( 2-34 ) and PTH ( 1-31 ) were less potent
Liu et al., Endocrinology 2002
(Second Messenger Systems) :
In cocultures of clonal marrow stromal cells ( MS1 ) and normal mouse spleen cells, both 1,25-dihydroxyvitamin D3 and rat
PTH ( rPTH ) - ( 1-34 ) can
induce the formation of tartrate-resistant
acid phosphatase- and calcitonin receptor positive multinucleated osteoclast-like cells, which can attach to dentine slices and produce resorption pits
Lai et al., Mol Cell Biochem 2006
(Bone Resorption) :
The presence of
parathyroid hormone ( PTH ; 10 ( -7 ), M ), a bone resorbing factor,
caused a significant decrease in calcium content and a corresponding elevation in medium glucose consumption, lactic acid production or tartrate-resistant
acid phosphatase ( TRACP ) activity in the diaphyseal or metaphyseal tissues
Wang et al., Sheng Li Xue Bao 2007
(Bone Resorption) :
In addition, sRANK significantly inhibited
PTH induced mRNA expression of carbonic anhydrase II and tartrate-resistant
acid phosphatase in murine bone marrow cells as confirmed by using semi-quantitative RT-PCR
Luben et al., Endocrinology 1976
:
Parathormone stimulated
acid phosphatase and hyaluronate synthesis by 100-200 % only in the CT cells ; in inhibited alkaline phosphatase, citrate decarboxylation, and prolyl hydroxylase by 75-90 % only in the PT cells
Broulik et al., Calcif Tissue Int 1991
(Bone Resorption) :
Hydrochlorothiazide inhibits
parathormone stimulated increase in plasma tartrate-resistant
acid phosphatase in mice
Xue et al., Am J Physiol Endocrinol Metab 2012
(Hyperparathyroidism) :
In the absence of CaSR, the
PTH stimulated expression of receptor activator of nuclear factor-?B ligand and tartrate-resistant
acid phosphatase and PTH stimulated osteoclastogenesis was also reduced
Pierce et al., Res Commun Chem Pathol Pharmacol 1985
:
Bone cell
acid phosphatase activity and lactic acid production are
stimulated by
parathyroid hormone or vitamin D3
Hall et al., J Pharmacol Exp Ther 1986
(Bone Resorption) :
Both
PTH and DBcAMP significantly
enhanced calvarial
acid phosphatase activity relative to control values [ PTH T/C = 1.48 ; DBcAMP T/C = 1.30 ]
Roodman et al., Proc Natl Acad Sci U S A 1985
:
This activity was increased by 1,25-dihydroxyvitamin D3 and
parathyroid hormone , and calcitonin
inhibited the increase in
acid phosphatase activity stimulated by these compounds
Wong et al., Calcif Tissue Int 1983
:
The OC characteristics (
acid phosphatase activity and hyaluronate synthesis, and their
stimulation by
PTH ) were recovered in the cell populations released early from calvariae, but these also contained OB cells and numerous spindle shaped alkaline phosphatase positive cells that resembled fibroblasts
Torres et al., Miner Electrolyte Metab 1993
:
In the present work, we studied the
effect of bovine
PTH ( bPTH ) ( 1-34 ) and PTHrP ( 1-34 ) on tartrate-resistant
acid phosphatase ( TRAP ), a marker of bone resorption, and alkaline phosphatase ( AP ) activities, and basal and vitamin D-stimulated osteocalcin ( BGP ) synthesis ( markers of bone formation ) in fetal rat calvaria cultures