Gene interactions and pathways from curated databases and text-mining

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FGFR3 — PI3

Text-mined interactions from Literome

Hart et al., Oncogene 2000 (Cell Transformation, Neoplastic) : Finally, we demonstrate that FGFR1, FGFR3 , and FGFR4 derivatives can stimulate PI-3 kinase activity
Serck-Hanssen et al., Ann N Y Acad Sci 2002 : The PI 3-kinase inhibitor, wortmannin, diminished the Ach response, consistent with activation of the PKCs by the upstream PI 3-kinase dependent phosphoinositide dependent kinase, PDK1
Mavila et al., PloS one 2012 (Liver Neoplasms) : FGF Receptor ( R ) activation resulted in the downstream activation of MAPK, PI3K-AKT , and ß-catenin pathways, as well as cellular proliferation