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FGFR3 — PI3
Text-mined interactions from Literome
Hart et al., Oncogene 2000
(Cell Transformation, Neoplastic) :
Finally, we demonstrate that FGFR1,
FGFR3 , and FGFR4 derivatives can
stimulate PI-3 kinase activity
Serck-Hanssen et al., Ann N Y Acad Sci 2002
:
The
PI 3-kinase inhibitor, wortmannin,
diminished the
Ach response, consistent with activation of the PKCs by the upstream PI 3-kinase dependent phosphoinositide dependent kinase, PDK1
Mavila et al., PloS one 2012
(Liver Neoplasms) :
FGF Receptor ( R ) activation
resulted in the downstream activation of MAPK,
PI3K-AKT , and ß-catenin pathways, as well as cellular proliferation