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CSE — PTGS2

Text-mined interactions from Literome

Shin et al., Toxicol Appl Pharmacol 2004 (Adenocarcinoma...) : Both antisense of c-myc and alpha-difluoromethylornithine ( DFMO, specific ODC inhibitor ) inhibited cell proliferation without affecting COX-2 expression in response to cigarette smoke extracts (CSE)
Martey et al., Am J Physiol Lung Cell Mol Physiol 2005 : Herein, we report the central role of the aryl hydrocarbon receptor (AHR) in cigarette smoke extract (CSE) induced COX-2 , microsomal PGE ( 2 ) synthase ( mPGES ), and PGE ( 2 ) production in human lung fibroblasts
Vassallo et al., J Immunol 2005 : CSE also induced cyclooxygenase-2 protein levels in maturing DCs and significantly augmented endogenous PGE2 release
Pei et al., Zhonghua Jie He He Hu Xi Za Zhi 2009 : CSE induced ECV-304 cell apoptosis and COX-2 expression in a dose dependent manner ... Furthermore CSE induced both apoptosis rate and COX-2 expression time-dependently, with the apoptosis rate achieving the peak after 24 h ( 8.87+/-0.41 ) %, while COX-2 expression reached the highest level at 9 h ... CSE induces endothelial cell apoptosis and increases the expression of COX-2 protein in vascular endothelial cells
Profita et al., Am J Physiol Lung Cell Mol Physiol 2010 (Pulmonary Disease, Chronic Obstructive) : These results suggest that CSE promote the induction of COX-2 and contributes to the proinflammatory effects of PGE ( 2 ) in the airways of COPD subjects
Wu et al., J Ethnopharmacol 2011 : The inhibition of COX-2 transcription was found to be related with the CSE inhibition of the p65/p50-driven transactivation of the COX-2 promoter
Kim et al., Am J Physiol Lung Cell Mol Physiol 2012 : MSC-CM also restored expression of ECM proteins and collagen gel contraction while suppressing CSE induced expression of cyclooxygenase-2 and microsomal PGE ( 2 ) synthase-2