Gene interactions and pathways from curated databases and text-mining

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CNR1 — FGFR3

Text-mined interactions from Literome

Steffens et al., Neuroscience 2003 : The results show that activation of CB1 cannabinoid receptors leads to inhibition of ACh release in the human and mouse neocortex
Schlicker et al., Br J Pharmacol 2003 : Furthermore, the effect of WIN 55,212-2 on NA release in the vas deferens and on cortical Ach release involves CB1 receptors, whereas the involvement of non-CB1-non-CB2 receptors can be excluded
Capasso et al., The open biochemistry journal 2009 : Several pharmacological studies indicate that CB1 cannabinoid receptors (CB1Rs) are present in guinea pig ileum (GPI) and their activation reduce the acetylcholine (Ach) release
Coutts et al., Br J Pharmacol 1997 : 4. The ( - ) -enantiomer of WIN 55212, was approximately 300 times less active than the ( + ) enantiomer in inhibiting the twitch response, had no CB1 antagonist activity against the active isomer and did not inhibit the release of ACh in the presence of physostigmine