Gene interactions and pathways from curated databases and text-mining

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HIF1A — MMP17

Text-mined interactions from Literome

Luo et al., BJU Int 2006 (Neoplasm Invasiveness...) : The expression of E-cadherin, vimentin, cathepsin D, MMP-2 and uPAR, which are proteins with established roles in the pathophysiology of invasion, could be regulated by HIF-1alpha in human prostate cancer cells
Kang et al., Clin Exp Pharmacol Physiol 2009 (Diabetes Mellitus, Experimental...) : Impairment of ischaemia induced EPC mobilization in the diabetic mouse model is associated with altered HIF-1 alpha/VEGF and MMP/TIMP regulation and represents a novel mechanism underlying defective postischaemic neovascularization in diabetes
Huang et al., Neoplasia (New York, N.Y.) 2009 (Anoxia...) : Activation of SLUG, a transcriptional factor regulating the EMT process of human cancers, by HIF-1alpha was critical for the induction of MT4-MMP under hypoxia