Gene interactions and pathways from curated databases and text-mining

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CD79A — NFKB1

Text-mined interactions from Literome

Petro et al., J Biol Chem 2001 : Moreover, activation of NF-kappaB in response to BCR signaling is completely abolished in B cells deficient for PLC-gamma2
Bone et al., Int Immunol 2001 : Nuclear NF-kappaB is induced in B cells by engagement of either the BCR or CD40 or by stimulation with lipopolysaccharide (LPS)
Korus et al., Oncogene 2002 (MAP Kinase Signaling System) : NF-kappaB activation by Bcr is not mediated by nuclear translocation, but rather by p38 mitogen activated protein kinase ( MAPK ) -dependent modification of the RelA/p65 transactivation domain
Hanson et al., J Biol Chem 2003 : Consistent with this, evidence has been presented that NF kappa B activity is required for Ras and BCR-ABL to transform cells ... The data presented here indicate that BCR-ABL expression in 32D myeloid cells or oncogenic Ras expression in murine fibroblasts blocks the ability of tumor necrosis factor (TNF) to activate NF kappa B
Lin et al., Semin Immunol 2004 (Lymphoma, B-Cell, Marginal Zone) : Recent studies demonstrate that CARMA1, a scaffold protein, plays an essential role in mediating TCR- or BCR induced NF-kappaB activation by recruiting two adaptor proteins, Bcl10 and MALT1, to lipid rafts following stimulation of antigen receptors
Xing et al., J Exp Med 2005 : G5pr(-/-) B cells did not show abnormalities in the BCR mediated activation of Erks and NF-kappaB , cyclin D2 induction, or Akt activation
Pappu et al., Eur J Immunol 2006 : NF-kappaB activation through B cell receptor (BCR) ligation is critical for B cell development, survival and antigen mediated activation of B cells
Duncan et al., Mol Cancer Ther 2008 : Additionally, we reported previously that BCR-ABL activates the transcription factor nuclear factor-kappaB (NF-kappaB) in a manner dependent on Ras and that inhibition of NF-kappaB by expression of a modified form of IkappaBalpha blocked BCR-ABL-driven tumor growth in a xenograft model ... These data indicate that blockage of BCR-ABL induced NF-kappaB activation via IkappaB kinase beta inhibition represents a potential new approach for treatment of Imatinib- or Dasatinib-resistant forms of chronic myelogenous leukemia
Schuman et al., Blood 2009 : However, the role of TAK1 in B-cell receptor (BCR) mediated NF-kappaB activation and B-cell development is not clear ... Thus, TAK1 is critical for B-cell maturation and BCR induced NF-kappaB activation
Xiao et al., Clin Immunol 2009 (Glomerulonephritis, IGA) : IgA-HMC conditioned medium up-regulated expression of ICAM-1, IL-6 and ATR1 and activated NF-kappaB and ERK1/2 in PTEC
Hoek et al., J Immunol 2009 (Lymphopenia) : Recent studies have shown that BCR signaling positively regulates NF-kappaB2 , suggesting BCR regulation of BR3 signaling
Colombo et al., PloS one 2012 (Lupus Erythematosus, Systemic...) : The effect of LAIR1 ligation by specific monoclonal antibodies, collagen or collagen producing mesenchymal stromal cells from reactive lymph nodes or bone marrow on Ig production by pokeweed mitogen and B cell receptor (BCR) mediated NF-kB activation was assessed by ELISA and TransAM assay
Hamdane et al., Oncogene 1997 : Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line ( P210BCR-ABL activates p65 NF-kappaB ) ... We have analysed the effect of p210BCR-ABL expression on NF-kappaB activity in DA1 cells ( an IL-3 dependent murine myeloid progenitor cell line ) ... A specific stimulation of NF-kappaB activity by kinase-active wild-type p210BCR-ABL has been evidenced by transcriptional activation assays