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IL1RAP — NFKB1

Pathways - manually collected, often from reviews:

• NCI Pathway Database IL1-mediated signaling events: NF kappa B1 p50 (NFKB1) → IL1 beta fragment/IL1R1/IL1RAP/PI3K complex (IL1B-IL1R1-IL1RAP-PIK3CA-PIK3R1) (modification, collaborate)
  Sizemore et al., Mol Cell Biol 1999, Reddy et al., J Biol Chem 1997
  Evidence: mutant phenotype, physical interaction

Text-mined interactions from Literome

Huang et al., Proc Natl Acad Sci U S A 1997 : Overexpression of an IL-1RAcP mutant lacking its intracellular domain, the IRAK binding domain, prevented the recruitment of IRAK to the receptor complex and blocked IL-1 induced NF-kappaB activation
Zetterström et al., Eur Cytokine Netw 1998 (Fever) : Interleukin-1 mediated febrile responses in mice and interleukin-1 beta activation of NFkappaB in mouse primary astrocytes, involves the interleukin-1 receptor accessory protein