Gene interactions and pathways from curated databases and text-mining

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ECM1 — TGFB3

Text-mined interactions from Literome

Bodo et al., J Dent Res 1999 (Cleft Lip...) : In the present report, we studied TGFalpha, TGFbeta1, and TGFbeta3 expressions and their effects on ECM macromolecule production of normal and cleft palatal fibroblasts in vitro, to investigate the mechanisms by which the phenotypic modulation of fibroblasts occurs during the cleft palate process
Czuwara-Ladykowska et al., J Biol Chem 2002 (Fibrosis) : Because of the prominent role of transforming growth factor beta ( TGF-beta ) in ECM synthesis, this study was undertaken to determine the possible interactions between Ets1 and the TGF-beta pathway
Daian et al., J Invest Dermatol 2003 (Keloid) : Insulin-like growth factor-I enhances transforming growth factor-beta induced extracellular matrix protein production through the P38/activating transcription factor-2 signaling pathway in keloid fibroblasts
Li et al., Zhonghua Yi Xue Za Zhi 2006 : To investigate the effects of bone morphogenetic protein (BMP)-7 on the extracellular matrix ( ECM ) accumulation induced by transforming growth factor ( TGF ) -beta
Newman et al., Birth Defects Res C Embryo Today 2007 : First, a `` core mechanism '' for precartilage mesenchymal condensation is described, based on positive autoregulation of the morphogen transforming growth factor ( TGF ) -beta , induction of the extracellular matrix ( ECM ) protein fibronectin, and focal accumulation of cells via haptotaxis
Shimizu et al., J Gastroenterol Hepatol 2008 (Fibrosis...) : Platelet derived growth factor ( PDGF ) is a potent stimulator of PSC proliferation, and transforming growth factor-beta , PDGF, and basic fibroblast growth factor stimulate ECM synthesis by PSC
Lei et al., Acta Pharmacol Sin 2008 : Transforming growth factor beta 3 ( TGF-beta3 ) combined with insulin-like growth factor I (IGF-I) induced the cartilage-specific collagen type II, aggrecan expression and extracellular matrix ( ECM ) accumulation at the end of a 3-week culture
Beyer et al., Arthritis Res Ther 2009 (Disease Progression...) : Hypoxia stimulates the production of ECM proteins by SSc fibroblasts in a transforming growth factor-beta dependent manner
Andersen et al., Scand J Immunol 2012 (Scleroderma, Diffuse) : Disturbed transforming growth factor beta ( TGFß ) signalling leads to enhanced synthesis of extracellular matrix ( ECM ) , which is manifested as systemic sclerosis ( SSc ), but this may be attenuated by the melanocortin system
Talts et al., J Cell Sci 1995 (Kidney Neoplasms...) : Regulation of mesenchymal extracellular matrix protein synthesis by transforming growth factor-beta and glucocorticoids in tumor stroma
Kopp et al., Lab Invest 1996 (Glomerulonephritis...) : Several lines of evidence suggest that local production of transforming growth factor-beta ( TGF-beta ) contributes to renal disease, particularly to the accumulation of the extracellular matrix protein that characterizes glomerulosclerosis and interstitial fibrosis