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CTLA4 — IL3
Text-mined interactions from Literome
Blazevic et al., J Clin Immunol 2001
:
Inhibition studies using the B7-binding fusion protein CTLA4Ig and antibodies against CD80 and CD86 demonstrate that
CTLA4Ig and anti-CD86
inhibited influenza-specific T cell proliferation,
interleukin (IL)-2 and interferon (IFN)-gamma production, and generation of influenza-specific CD8+ CTL
Alegre et al., J Immunol 1998
:
Inhibition of binding of
CTLA-4 to its ligands using soluble anti-CTLA-4 mAb during stimulation with Ag
increased the production not only of IL-2 by Th1 clones, but also that of IL-3 and IFN-gamma by Th1 clones and of
IL-3 , IL-4, IL-5, and IL-10 by Th2 clones