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BRD1 — TP53
Text-mined interactions from Literome
Saha et al., J Virol 2011
(Epstein-Barr Virus Infections) :
Subsequently, we demonstrated that EBNA3C significantly suppresses both the ING4- and
ING5 mediated regulation of
p53 transcriptional activity in a dose dependent manner
Gerona-Navarro et al., J Am Chem Soc 2011
:
Our results strongly argue that these CBP modulators can effectively
inhibit p53 transcriptional activity by blocking p53K382ac binding to CBP
BRD and promoting p53 instability by changes of its post-translational modification states, a different mechanism than that of the p53 inhibitors reported to date