Gene interactions and pathways from curated databases and text-mining

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CCND1 — SETD2

Text-mined interactions from Literome

Wen et al., Cancer Res 2010 (Lung Neoplasms) : Overexpression of the dominant negative mutant of HIF-1alpha ( DN-HIF ) significantly enhanced cyclin D1 expression upon hypoxia or arsenite exposure, suggesting the negative regulation of cyclin D1 by HIF-1 ... Chromatin immunoprecipitation assay revealed that HIF-1 was able to directly bind to the promoter region of cyclin D1, which indicates that the negative regulation of cyclin D1 by HIF-1 is through a direct mechanism
Zhang et al., Medicina (Kaunas) 2012 (Anoxia) : CCND1 ( cyclin D1 ) expression could be regulated by PPAR? and HIF-1a via the cell cycle pathway