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IL6 — MAF

Text-mined interactions from Literome

Yang et al., J Immunol 2005 (Calcium Signaling) : c-Maf induction requires both IL-6- and TCR initiated signals, and is independent of IL-4/Stat6 signals ... IL-6 induces similar c-Maf expression in protein kinase Ctheta-deficient CD4 ( + ) T cells
Hiramatsu et al., J Leukoc Biol 2010 : We found that IL-6 induced c-Maf expression in CD4 ( + ) T cells and that the enforced expression of c-Maf induced IL-21 production in CD4 ( + ) T cells without IL-6, IL-4/STAT6 signaling, or an autocrine effect of IL-21 ... On the other hand, we also found that although TGF-beta up-regulated IL-6 induced c-Maf expression in CD4 ( + ) T cells, TGF-beta inhibited c-Maf induced IL-21 production in CD4 ( + ) T cells
Rani et al., J Immunol 2011 : Furthermore, IL-2 and IL-6 synergistically induced C-MAF expression in TCR activated T cells, suggesting functional cooperation between these cytokines