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ABCC1 — ATP5O

Text-mined interactions from Literome

Vaidya et al., Mol Pharm 2009 : DNP-SG efflux decreased by 69.1 ( +/-11.3 ) %, 51.1 ( +/-5.4 ) %, 56.7 ( +/-8.3 ) % and 53.6 ( +/-10.8 ) % ( p < 0.05 ) in the presence of 5 mM sodium orthovanadate ( ATPase inhibitor ), 100 microM MK571 ( MRP-inhibitor ), 1 mM dipyridamole ( BCRP/P-gp/MRP1-inhibitor ) and 100 microM verapamil ( P-gp/MRP1 inhibitor ) respectively, without any change in DNP-SG formation, total tissue glutathione, GSH/GSSG ratio, tissue integrity or tissue viability
Laughlin et al., Int J Biol Macromol 2010 : Whereas MRP-amide inhibited ATPase essentially completely ( approximately 96 % inhibition ), carein 1.8 did not inhibit at all ( 0 % inhibition )
Megaraj et al., Pharmacogenet Genomics 2011 : Examination of substrate stimulated MRP2 dependent ATPase activity of S789F and A1450T, SNPs located in MRP2 nucleotide binding domains ( NBDs ), demonstrated significantly decreased ATPase activity and only modestly decreased affinity for ATP compared with WT