Gene interactions and pathways from curated databases and text-mining

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AKT2 — PTH

Text-mined interactions from Literome

Gentili et al., J Cell Biochem 2002 (MAP Kinase Signaling System) : PTH causes a rapid ( 0.5-5 min ) phosphorylation of Akt/PKB, effect that was abrogated by PI3K inhibitors, indicating that in rat enterocytes, PI3K is an upstream mediator of Akt/PKB activation by PTH
Chang et al., Mol Cell Endocrinol 2009 : PTH ( 10 nM, 24 h ) treatment induced a reduction in insulin stimulated glucose uptake, AKT activity ( phosphorylated AKT/total AKT protein expression ) and a decrease in GLUT4 and IRS-1 protein expression compared to vehicle treated controls in differentiated adipocytes
Calvo et al., Biochim Biophys Acta 2010 : PTH treatment induces an association of AKT with the catalytic subunit of PP2A and increases its phosphatase activity