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ESR1 — KISS1

Text-mined interactions from Literome

Smith et al., Endocrinology 2005 (Body Weight) : In the Arc, the effects of T on KiSS-1 mRNA were completely mimicked by estrogen but only partially mimicked by dihydrotestosterone, a nonaromatizable androgen, suggesting that both estrogen receptor ( ER ) and androgen receptor (AR) play a role in T-mediated regulation of KiSS-1
Li et al., Endocrinology 2007 : Together, these results demonstrate that E ( 2 ) -dependent transcriptional activation of KiSS1 gene is mediated by ERalpha through the interaction of Sp1/Sp3 proteins with the GC-rich motifs of KiSS1 promoter, providing a molecular mechanism of how steroid hormone feedback regulates KiSS1 expression