Gene interactions and pathways from curated databases and text-mining

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NM — RAC1

Text-mined interactions from Literome

Filippi et al., Blood 2007 (Emphysema...) : Rho GTPase Rac1 is critical for neutrophil migration into the lung ... The role of Rac1 in neutrophil migration related to inflammatory processes has remained elusive and has yet to be determined in physiologic in vivo models ... We examined the specific role of Rac1 in neutrophil migration into the lung during the inflammatory process induced by formyl-methionyl-leucyl-phenylalanine exposure
Katsube et al., J Leukoc Biol 2008 : The studies with pharmacological inhibitors suggest that calpain inhibition mediated neutrophil migration is mediated by activation of MEK/ERK, p38, JNK, PI-3K/Akt, and Rac