Gene interactions and pathways from curated databases and text-mining

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RAC1 — UTP3

Text-mined interactions from Literome

Seye et al., J Biol Chem 2004 (Arteriosclerosis) : Using a binding assay to measure the activity of the small GTPases Rho, we found that stimulation of HCAEC by UTP increased the activity of RhoA and Rac1 ( but not Cdc42 )
Bagchi et al., J Biol Chem 2005 : Here we show that mutation of the RGD sequence to RGE in the human P2Y(2)R expressed in 1321N1 astrocytoma cells completely prevented UTP induced chemotaxis as well as activation of G ( o ), Rac , and Vav2, a guanine nucleotide exchange factor for Rac