◀ Back to TYR

PTPN1 — TYR

Text-mined interactions from Literome

Liang et al., J Biol Chem 2005 : We show that down-regulation of PTP1B activity with small molecule inhibitors suppresses cell spreading and migration to fibronectin, increases Tyr ( 527 ) phosphorylation in Src, and decreases phosphorylation of FAK, p130 ( Cas ), and ERK1/2
Stuible et al., J Biol Chem 2008 (Diabetes Mellitus...) : PTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446
Basavarajappa et al., Mol Cell Biol 2011 : Phosphorylation of Tyr-347 in the BPS domain of Grb14 is critical for interaction with PTP1B , resulting in the competitive inhibition of PTP1B activity
Bettaieb et al., J Biol Chem 2013 (Glucose Intolerance...) : Importantly, PTP1B pharmacological inhibition increased PKM2 Tyr-105 phosphorylation and decreased PKM2 activity