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COL1A2 — YBX1

Text-mined interactions from Literome

Higashi et al., J Biol Chem 2003 : Overexpression of YB-1 in human dermal fibroblasts decreased steady state levels of COL1A2 mRNA and repressed COL1A2 promoter activity in a dose dependent manner ... This inhibitory effect of YB-1 on COL1A2 expression was abolished by mutations of the IgRE shown to prevent YB-1 binding in EMSA
Higashi et al., J Biol Chem 2003 : They also indicate that IFN-gamma/YB-1 inhibits COL1A2 transcription by dual actions : via the IFN-gamma response element and through a cross-talk with the TGF-beta/Smad signaling pathway