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HSP90AA1 — NOX5
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Chen et al., Antioxid Redox Signal 2011
:
Hsp90 regulates
NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production ... Long-term
Hsp90 inhibition
reduced Nox5 expression and provides further evidence that Nox5 is an Hsp90 client protein
Chen et al., Arterioscler Thromb Vasc Biol 2012
:
Hsp90 inhibitors did not alter Nox5 micro RNA levels, and proteasome inhibition
prevented Nox2 and 5 protein degradation and increased ubiquitin incorporation ... We conclude that
Hsp90 binds to and
regulates Nox protein stability