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BRD8 — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Gerona-Navarro et al., J Am Chem Soc 2011
:
Our results strongly argue that these CBP modulators can effectively
inhibit p53 transcriptional activity by blocking p53K382ac binding to CBP
BRD and promoting p53 instability by changes of its post-translational modification states, a different mechanism than that of the p53 inhibitors reported to date
Blagosklonny et al., Biochem Biophys Res Commun 1998
:
However, induction of
p120 was independent of p53 ; and expression of exogenous wt
p53 induced p21WAF1/CIP1 but not p120, excluding p120 as a transcriptional target of p53