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CD80 — IL12A

Text-mined interactions from Literome

Foss et al., Infect Immun 1999 : LPS and CT each induced IL-1beta expression in macrophages, while only LPS induced IL-12 and only CT induced CD80-CD86
Thomas et al., Int J Cancer 2000 (Carcinoma, Squamous Cell...) : Our results provide evidence that regression of oral head-and-neck SCC may be induced by therapy with systemic IL-12 and that expression of the CD80 co-stimulatory molecule by SCC and IFN-gamma by the host promote IL-12 induced regression of SCC
Gutzmer et al., Immunology 2004 : After up-regulation of the C3aR by IFN-alpha+ IFN-gamma, C3a significantly up-regulated the surface expression of CD54, CD83 and CD86, but not of CD40, CD80 or human leucocyte antigen ( HLA ) -DR. C3a had no effect on the production of interleukin (IL)-10 or IL-12p70 , or on the capacity of MoDC to stimulate autologous T-cell proliferation
Pedraza-Sánchez et al., Int Immunopharmacol 2006 : The early activation marker CD69 was induced at 4 h in NK cells > B cells > T cells > monocytes whereas at 24 h CD80 and CD86 levels were augmented on monocytes and IL-12 was induced ; HLA-DR levels increased on both B cells and monocytes
Yoon et al., Mol Pharmacol 2006 : In the presence of apigenin, CD80 , CD86, and major histocompatibility complex class I and II molecules, expressions on DC were significantly suppressed, and lipopolysaccharide (LPS) induced interleukin (IL)-12 expression was impaired
Shi et al., Arch Dermatol Res 2007 : We demonstrate that after treatment with PS, murine DCs display reduced expression of MHC II, CD80 , CD86 and CD40, but increased programmed death ligand-1 ( PD-L1 and PD-L2 ) ; and increased IL-10 and inhibited IL-12 cytokine production
Steers et al., Vaccine 2008 : L ( LA ) enhanced the surface expression of MHC class I, class II, CD80 , and CD86 molecules, induced the secretion of IFN-gamma, IL-12p40 , TNF-alpha and IL-10, and caused a shift in the proteasome profile from constitutive to immunoproteasomes as observed by the induction of beta2i, beta5i, PA28alpha, and PA28beta subunits
Zhang et al., Acta Pharmacol Sin 2009 : IL-12 suppression, enhanced endocytosis and up-regulation of MHC-II and CD80 in dendritic cells during experimental endotoxin tolerance
Chen et al., Immunol Lett 2012 (Liver Neoplasms...) : We found that Tregs derived from the tumor mice down-regulated the expression of costimulatory molecules CD80/CD86 on DCs and inhibited the production of TNF-a and IL-12 from DCs
Xue et al., Int Immunopharmacol 2013 : We elucidated that IFN-? up-regulated the expression of MHC II, CD40, CD80 , CD83 and CD86 molecules on BMDCs, down-regulated the activity of pinocytosis and phagocytosis by BMDCs, and induced higher levels of IL-12 and TNF-a secreted by BMDCs
Kelleher et al., Int Immunol 1998 : IL-12 increases CD80 expression and the stimulatory capacity of bone marrow derived dendritic cells
Suemoto et al., J Dermatol Sci 1998 : The expression of MHC class II, CD80 and CD86 on EC was not affected by IL-12