Gene interactions and pathways from curated databases and text-mining

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CCL2 — HSPG2

Text-mined interactions from Literome

Stokes et al., J Immunol 2007 : We could find no evidence for these pathways being involved in the P2Y(2)R induced increase in mRNA levels although inhibition of PLC blocked the UTP induced increased release of MCP-1
Fantuzzi et al., Blood 2008 (HIV Infections) : In this study, we show for the first time that the phosphatidylcholine-specific phospholipase C ( PC-PLC ) is required for the production of CCL2 triggered by gp120 in human monocyte derived macrophages ( MDMs ) ... Furthermore, PC-PLC is required for NF-kB mediated CCL2 production triggered by R5 gp120
Spadaro et al., PloS one 2013 : In this study, we show for the first time that phosphoinositide-specific phospholipase C ( PI-PLC ) is required for the production of CCL2 triggered by gp120 in macrophages