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HSPG2 — LPA

Text-mined interactions from Literome

Oh et al., Mol Cell Biol 2004 : Moreover, the stable expression of NHERF2 potentiated LPA induced phospholipase C-beta (PLC-beta) activation, which was markedly attenuated by either a mutation in the PDZ binding motif of LPA ( 2 ) or by the gene silencing of NHERF2
Choi et al., Biochim Biophys Acta 2004 : In the current study, we demonstrate that stable expression of exogenous E3KARP increases LPA induced phospholipase C (PLC) activation and subsequent elevation of intracellular Ca ( 2+ ) in opossum kidney proximal tubule ( OK ) cells ... From these results, we suggest that E3KARP plays a necessary role in LPA induced PLC activation, and that PLC dependent elevation of intracellular Ca ( 2+ ) but not PKC activation is necessary for the LPA induced increase of NHE3 exocytosis
Lee et al., Mol Cell Biol 2013 : We describe novel findings that lysophosphatidic acid (LPA) regulates PLC-ß1 and PLC-ß2 via two distinct pathways to enhance intestinal epithelial cell ( IEC ) proliferation and migration that facilitate wound closure and recovery of the intestinal epithelial barrier
Hofer et al., Curr Biol 1998 : Ral was activated by the Ca2+ ionophore ionomycin, and activation by LPA or EGF could be blocked by a phospholipase C (PLC) inhibitor