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HSPG2 — PKD3

Text-mined interactions from Literome

Luangwedchakarn et al., Peptides 2003 : Furthermore, a phospholipase C (PLC) selective inhibitor, U-73122, completely blocks the phosphorylation of PKD/PKCmu by CKS-17 while a negative control U-73343 does not
Wood et al., J Biol Chem 2005 : Antigen receptor activation of wild type PKD is dependent on phospholipase C (PLC)/diacylglycerol ( DAG ) and PKC, whereas PKD-S744E/S748E is only dependent on PLC/DAG but no longer requires PKC ... In lymphocytes, PKD1 is, thus, not regulated by PLC and PKC in a linear pathway ; rather, PKD1 activation has more stringent requirements for integration of dual PLC signals, one mediated by PKCs and one that is PKC independent
Qin et al., J Biol Chem 2006 : Whereas G protein Gbetagamma subunits were required for both PKD serine phosphorylation and tyrosine phosphorylation, intracellular Ca ( 2+ ) mobilization was required for VEGF-A ( 165 ) -stimulated PKD tyrosine phosphorylation and phospholipase C (PLC) activity was required for PKD serine phosphorylation ... Surprisingly, the PLC inhibitor did not inhibit PKD tyrosine phosphorylation