Gene interactions and pathways from curated databases and text-mining

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E2F1 — RELA

Text-mined interactions from Literome

Tanaka et al., Mol Cell 2002 : In these clones, E2F1 inhibited NF-kappaB activity by binding to its subunit p65 in competition with a heterodimeric partner p50 ... In these clones, E2F1 inhibited NF-kappaB activity by binding to its subunit p65 in competition with a heterodimeric partner p50 ... In addition to overexpressed E2F1, endogenous E2F1 released from Rb was also found to inhibit NF-kappaB activity in a cell cycle dependent manner by using E2F1 ( +/+ ) and E2F1 ( -/- ) murine embryonic fibroblasts
Wan et al., Immunity 2003 : The inhibition of NFkappaB in antigen stimulated T cells results in apoptosis but does not inhibit E2F activation and S phase entry
Matsumura et al., Cell cycle (Georgetown, Tex.) 2003 : c-Myc and E2F1 inhibit NF-kappaB activities induced by TNFalpha or reactive oxygen species
Kundu et al., J Biol Chem 1997 : In vitro transcription assay demonstrates that E2F-1 represses NF-kappaB mediated transcription in a cell-free system