Gene interactions and pathways from curated databases and text-mining

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JAK1 — MMP10

Text-mined interactions from Literome

Ruiz et al., J Biol Chem 2011 (MAP Kinase Signaling System) : Furthermore, activation of DDR2, JAK2 , and ERK1/2 MAPK signaling pathways was essential for collagen I-induced DDR1 and matrix metalloproteinase 10 expression
Cui et al., Cell Signal 2012 : In conclusion, we demonstrated that CRP promoted MMP-10 expression and activity in cardiomyocytes, and clarified that c-Raf/MEK/ERK and JAK1/ERK signaling pathways were involved in MMP-10 expression regulation via activation of DNA binding sites for AP-1 and STAT3 in cardiomyocytes