Ying et al., Dev Biol 2001
(Digestive System Abnormalities) :
Previous studies have demonstrated that extraembryonic ectoderm derived BMP4 and BMP8B are both required for PGC generation ... These results suggest that PGC generation in the mouse embryo is regulated not only by extraembryonic ectoderm derived BMP4 and BMP8B, but also by endoderm derived BMP2
Ying et al., TheScientificWorldJournal 2002
:
Both bone morphogenetic proteins 4 (Bmp4) and 8b ( Bmp8b ) are expressed in the extraembryonic ectoderm and are required for PGC formation