Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ CD40 ▸ PTGS2 ▸ IL13 ▸
AHSA1 ▸ VEGFA ▸ TLR9 ▸ CA2 ▸ TLR1 ▸ CCL2 ▸ TLR8 ▸
TLR7 ▸ IL3 ▸ RNF19A ▸ TLR6 ▸ IL15 ▸ TGFB1 ▸ IL5 ▸
LTA ▸ TLR10 ▸ IL33 ▸ NOS2 ▸ TCF21 ▸ TCF4 ▸ F2RL1 ▸
IL18 ▸ TCF23 ▸ TCF24 ▸ IL22 ▸ TCF3 ▸ TCF20 ▸ TCF15 ▸
TCF12 ▸ TCF25 ▸ CRK ▸ TCF7 ▸ TCF19 ▸ PIK3R1 ▸ NFKBIA ▸
NA ▸ CSE ▸ PIK3CA ▸ LPA ▸ MMP9 ▸ IL1RN ▸ IL32 ▸
PAF1 ▸ HGF ▸ IL31 ▸ APOB ▸ EGF ▸ LEO1 ▸ CDC73 ▸
GRAP2 ▸ WDR61 ▸ CTR9 ▸ IL11 ▸ S100A8 ▸ IFNB1 ▸ MMP2 ▸
IL7 ▸ CXCR1 ▸ IL25 ▸ IL9 ▸ FGF2 ▸ IL19 ▸ ITGAM ▸
IL21 ▸ IL20 ▸ IL16 ▸ IL24 ▸ IL34 ▸ SAA1 ▸ IL27 ▸
POLDIP2 ▸ IL37 ▸ IL26 ▸ FAS ▸ MMP3 ▸ INS ▸ NOS1 ▸
EGFR ▸ MIF ▸ CXCR2 ▸ AKT3 ▸ CRP ▸ PI3 ▸ AKT1 ▸
ALB ▸ AKT2 ▸ NOX1 ▸ CD14 ▸ CALM3 ▸ CASP4 ▸ MMP13 ▸
MMP1 ▸ IKBKB ▸ CASP3 ▸ CASP16 ▸ CASP5 ▸ CASP9 ▸ CASP14 ▸
CASP12 ▸ CASP6 ▸ F2R ▸ CASP7 ▸ NOS3 ▸ CASP8 ▸ CASP2 ▸
CD40LG ▸ CASP10 ▸ NOX4 ▸ CASP1 ▸ NOX3 ▸ NOX5 ▸ PLG ▸
HMGB1 ▸ PTX3 ▸ PTK2 ▸ MYD88 ▸ TGFB2 ▸ NOD1 ▸ IGF1 ▸
PTK7 ▸ LIF ▸ SELE ▸ ITGB2 ▸ TNFSF10 ▸ PTK6 ▸ CHUK ▸
MYLIP ▸ GP9 ▸ ERVK-6 ▸ LEP ▸ IKBKG ▸ MUC1 ▸ IL12B ▸
GP6 ▸ MMP8 ▸ GP2 ▸ TREM1 ▸ GP5 ▸ MAP3K7 ▸ SRC ▸
STAT3 ▸ PRG3 ▸ CXCL12 ▸ PRG2 ▸ IFNA2 ▸ PTX4 ▸ PRG4 ▸
HNRNPH1 ▸ PRKAR1B ▸ VCAM1 ▸ LTB ▸ IFNA21 ▸ MMP7 ▸ SOD2 ▸
VIP ▸ PRKAR2A ▸ IFNA14 ▸ IFNA1 ▸ IFNA7 ▸ SERPINE1 ▸ PRKAR1A ▸
IFNA5 ▸ IL12A ▸ MPO ▸ SOD3 ▸ PTBP1 ▸ PRKACB ▸ PRKAR2B ▸
IFNA17 ▸ IFNA8 ▸ HNRNPF ▸ IFNA13 ▸ PTBP2 ▸ IFNA4 ▸ CRH ▸
CSF3 ▸ WNK1 ▸ HDAC2 ▸ IFNA16 ▸ IFNA6 ▸ PAM ▸ IFNA10 ▸
SOD1 ▸ PRKACG ▸ PLD2 ▸ S100A12 ▸ MMP14 ▸ MMP15 ▸ CXCL10 ▸
MMP10 ▸ MMP25 ▸ CAT ▸ CSK ▸ CCL3 ▸ EGR1 ▸ MMP24 ▸
SETD2 ▸ SPP1 ▸ TNFRSF1A ▸ MMP12 ▸ MMP20 ▸ FGF1 ▸ TGFB3 ▸
MMP26 ▸ MMP16 ▸ EDN1 ▸ IL1R1 ▸ MMP19 ▸ MSH3 ▸ MMP17 ▸
MMP27 ▸ NOD2 ▸ PLD1 ▸ MMP11 ▸ ELANE ▸ MMP28 ▸ HDAC1 ▸
MMP21 ▸ MSH2 ▸ MSH5 ▸ AHR ▸ CD8A ▸ PLD6 ▸ QRICH2 ▸
PLA2G1B ▸ PLD5 ▸ NAALADL1 ▸ SST ▸ PLD4 ▸ FGF7 ▸ FASLG ▸
MAP2K1 ▸ MSH4 ▸ PLD3 ▸ TRAF6 ▸ MSH6 ▸ QRICH1 ▸ TAB1 ▸
SYT1 ▸ CD4 ▸ ANGPT2 ▸ STX2 ▸ FGF19 ▸ CSF1 ▸ FGF12 ▸
FGF14 ▸ FGF20 ▸ ITGB1 ▸ FGF3 ▸ SOCS3 ▸ FGF5 ▸ HMOX1 ▸
CD38 ▸ CSRP1 ▸ FGF17 ▸ HSPD1 ▸ FGF4 ▸ SELL ▸ FGF18 ▸
CD28 ▸ SAA2 ▸ HDAC3 ▸ CXCL1 ▸ P2RY6 ▸ PDLIM7 ▸ CD46 ▸
FGF22 ▸ FGF16 ▸ ETS1 ▸ PPARG ▸ FGF9 ▸ HDAC6 ▸ TNFSF12 ▸
FGF10 ▸ HDAC5 ▸ C1QB ▸ FGF23 ▸ RAC1 ▸ NGF ▸ SELP ▸
ADIPOQ ▸ FGF11 ▸ STAT1 ▸ FGF13 ▸ C1QA ▸ TXN ▸ FGF8 ▸
LTF ▸ FGF6 ▸ FGF21 ▸ SAA4 ▸ PDCD11 ▸ PRTN3 ▸ PLAU ▸
CD8B ▸ PF4 ▸ NPS ▸ RHO ▸ RBBP4 ▸ PPARA ▸ MUC19 ▸
MUC6 ▸ AGTR2 ▸ MUC22 ▸ CFTR ▸ MUC7 ▸ HSPG2 ▸ CXCR3 ▸
CR1 ▸ MUC16 ▸ ST8SIA2 ▸ CD79A ▸ TRPV1 ▸ MTX1 ▸ HDAC4 ▸
MUC2 ▸ CISH ▸ BCL3 ▸ MUC15 ▸ ANGPT1 ▸ MUC4 ▸ ECM2 ▸
TNFSF13B ▸ HDAC10 ▸ CPOX ▸ HSPB1 ▸ ITIH4 ▸ HDAC11 ▸ MUC12 ▸
APC ▸ TNMD ▸ MUC13 ▸ MUC21 ▸ NAP1L4 ▸ TAT ▸ MTOR ▸
ANG ▸ PRKCD ▸ STX1A ▸ HDAC8 ▸ PDGFB ▸ ECM1 ▸ MUC8 ▸
HDAC9 ▸ RHOA ▸ STAT4 ▸ HES1 ▸ CXCR4 ▸ PLA2G4A ▸ HDAC7 ▸
GPI ▸ RBBP7 ▸ IL2RA ▸ MUC20 ▸ MUC17 ▸ SETBP1 ▸ IL17F ▸
GRP ▸ LPL ▸ SIGLEC7 ▸ PRKAB1 ▸ MAP2K7 ▸ IBD8 ▸ PRR26 ▸
IBD2 ▸ ELF4 ▸ APEX1 ▸ HES4 ▸ PGF ▸ EMD ▸ EPO ▸
MPL ▸ PRKAA1 ▸ PRR21 ▸ CXCL17 ▸ CXCL9 ▸ DDIT3 ▸ PRKAA2 ▸
ADAM17 ▸ AZU1 ▸ CHI3L1 ▸ CALM2 ▸ UTP18 ▸ PRL ▸ IFI44 ▸
CXCL6 ▸ FCGR1A ▸ DEFA1 ▸ ROCK2 ▸ PRR12 ▸ CALM1 ▸ PAEP ▸
PRR25 ▸ UTP15 ▸ PRKAG2 ▸ PKD1 ▸ DUSP1 ▸ ARG1 ▸ HES7 ▸
ICAM4 ▸ FGA ▸ PRR24 ▸ FOXO3 ▸ ICOSLG ▸ NTS ▸ UTP23 ▸
IBD4 ▸ TAC3 ▸ BCL10 ▸ ETS2 ▸ PRR11 ▸ HES3 ▸ PRR7 ▸
PRR16 ▸ RENBP ▸ SMAD3 ▸ CCL20 ▸ HES6 ▸ PRKAG1 ▸ NUP43 ▸
UTP6 ▸ MUC5AC ▸ CTNNB1 ▸ IBD7 ▸ JAK2 ▸ HDC ▸ SELPLG ▸
IBD6 ▸ ICAM2 ▸ PRR14 ▸ PRR15 ▸ RELB ▸ TAC1 ▸ IBD9 ▸
TP53 ▸ OSM ▸ BCL2 ▸ CCR5 ▸ PRR5 ▸ IRAK1 ▸ NR0B1 ▸
TGFA ▸ BRAF ▸ ESR1 ▸ IBD3 ▸ HES5 ▸ TFPI ▸ PRR19 ▸
ICAM5 ▸ A2M ▸ NR4A2 ▸ ADAM11 ▸ PRR22 ▸ MT4 ▸ TF ▸
SEA ▸ CYP1A1 ▸ ARG2 ▸ PRR9 ▸ PRR4 ▸ MET ▸ PRDX2 ▸
MAP3K1 ▸ PRR18 ▸ PTAFR ▸ FGG ▸ ADCYAP1 ▸ ELF3 ▸ PRR3 ▸
HBEGF ▸ PRR13 ▸ HES2 ▸ CXCL11 ▸ IBD5 ▸ IRAK3 ▸ IL1R2 ▸
RNASE3 ▸ PGD ▸ PRKAB2 ▸ PRKCA ▸ MT3 ▸ TPO ▸ UTP20 ▸
UTP3 ▸ TAC4 ▸ ICAM3 ▸ MEFV ▸ ASIP ▸ TACR1 ▸ CSH1 ▸
GH1 ▸ HRAS ▸ GRB2 ▸ CAPN1 ▸ CDC42 ▸ CAPN8 ▸ ARSA ▸
NLRP3 ▸ TNP2 ▸ THBD ▸ GIP ▸ TRNAI1 ▸ C1orf228 ▸ IGF2 ▸
FUT11 ▸ CD44 ▸ FOXP3 ▸ APOA2 ▸ MYO10 ▸ IDO1 ▸ PTPN11 ▸
GRB10 ▸ SMAD5 ▸ SMAD4 ▸ APOA1 ▸ CD2 ▸ CCL4 ▸ NPY ▸
HCG11 ▸ VDR ▸ SMAD9 ▸ CPB1 ▸ HCG14 ▸ CAPN11 ▸ HMGB3 ▸
WNT1 ▸ WNT4 ▸ MYO16 ▸ ELAVL1 ▸ WNT16 ▸ HCG22 ▸ PDGFA ▸
PAK3 ▸ CYP19A1 ▸ HCG18 ▸ PAH ▸ CYP1A2 ▸ FUT8 ▸ CAPN5 ▸
SMAD6 ▸ TNFRSF9 ▸ FXYD1 ▸ HMGB4 ▸ FUT4 ▸ FUT7 ▸ AGTR1 ▸
CA1 ▸ TMSB4X ▸ CEBPA ▸ VCP ▸ CD86 ▸ HCG8 ▸ HCG17 ▸
AR ▸ CAPN12 ▸ WNT2 ▸ ADAM19 ▸ CXCL14 ▸ CAPN14 ▸ ITGA5 ▸
PINK1 ▸ CXCL13 ▸ ALOX5 ▸ HMGB2 ▸ NFKBIZ ▸ CTSB ▸ CXCR6 ▸
MAP2K3 ▸ ELF5 ▸ ATP8A2 ▸ SPP2 ▸ MRXS5 ▸ SCARB1 ▸ ABL1 ▸
PROK1 ▸ MAP2K2 ▸ NAMPT ▸ ALX1 ▸ F2RL2 ▸ FOXO1 ▸ OXA1L ▸
CXCL5 ▸ ADM ▸ ALX3 ▸ BMP2 ▸ CD1D ▸ FGB ▸ CCL5 ▸
GRB14 ▸ CSTA ▸ POU2F1 ▸ RAG1 ▸ PAK2 ▸ IL23A ▸ SMAD2 ▸
CGN ▸ PAK7 ▸ HCG25 ▸ RNASE2 ▸ FUT2 ▸ BCL6 ▸ CAPN3 ▸
DPM2 ▸ TNFRSF1B ▸ CAPN7 ▸ ELF2 ▸ PARK2 ▸ UCN2 ▸ GAL ▸
HRH1 ▸ VAV1 ▸ CSH2 ▸ CAPN13 ▸ RAC3 ▸ CD69 ▸ MAP2K4 ▸
ELF1 ▸ FUT6 ▸ HCG16 ▸ ANPEP ▸ ROCK1 ▸ FOXO4 ▸ CD163 ▸
CAPN15 ▸ HCG4 ▸ FMR1 ▸ CPB2 ▸ RAC2 ▸ HCG27 ▸ RETN ▸
MAP2K5 ▸ PARK7 ▸ JAK3 ▸ FUT10 ▸ MPG ▸ HCG24 ▸ KLRB1 ▸
HCG9 ▸ TEC ▸ CXCL3 ▸ PITX1 ▸ C3 ▸ RABEPK ▸ DNASE2 ▸
TNP1 ▸ TBP ▸ SFXN1 ▸ SERPINE2 ▸ NPY4R ▸ KRT10 ▸ CP ▸
FCER2 ▸ PAK4 ▸ KLK3 ▸ GRPR ▸ SLPI ▸ VASP ▸ APOE ▸
SOAT1 ▸ CDH5 ▸ NPY6R ▸ FUT5 ▸ SMAD1 ▸ GAST ▸ DPM3 ▸
STAT5A ▸ WNT11 ▸ MAPKAPK2 ▸ MTA2 ▸ MKNK1 ▸ PTGS1 ▸ CAPN10 ▸
IFIH1 ▸ FUT1 ▸ CAPN6 ▸ NR4A1 ▸ WNT6 ▸ HLA-DRB1 ▸ ADAM10 ▸
MBP ▸ PDCD4 ▸ CAPN9 ▸ TNFSF11 ▸ TPT1 ▸ SPESP1 ▸ FUT3 ▸
AREG ▸ BLM ▸ CNR2 ▸ JAK1 ▸ HCG15 ▸ FOXO6 ▸ DUOX1 ▸
MYO19 ▸ PTHLH ▸ SERPINB2 ▸ SYK ▸ MEPE ▸ MTA1 ▸ PAK1 ▸
HCG23 ▸ FUT9 ▸ CEACAM6 ▸ LBP ▸ BCR ▸ CDH1 ▸ DPM1 ▸
ALX4 ▸ HIF1A ▸ CXCL16 ▸ MTA3 ▸ WNT3 ▸ CNR1 ▸ CTSS ▸
TRAF2 ▸ HCG26 ▸ KSR2 ▸ MAP2K6 ▸ CXCL2 ▸ DNASE1 ▸ CEBPB ▸
GHRH ▸ CD83 ▸ BPI ▸ ACKR3 ▸ TSC22D3 ▸ MYO6 ▸ REL ▸
TNPO1 ▸ S100A9 ▸ FCGR2B ▸ CTGF ▸ HCG21 ▸ KDR ▸ HCG20 ▸
IRS1 ▸ DDX58 ▸ CEACAM1 ▸ DEFA1B ▸ GRB7 ▸ FGFR2 ▸ SMAD7 ▸
PGP ▸ F7 ▸ CAPN2 ▸ F10 ▸ GSTM1 ▸ CX3CL1 ▸ HBD ▸
PTPN22 ▸ FOSL1 ▸ PAK6 ▸ HCAR1 ▸ MCHR1 ▸ NPBWR2 ▸ HRH3 ▸
GNAI1 ▸ HRH4 ▸ S1PR3 ▸ OXGR1 ▸ HEBP1 ▸ CCL28 ▸ FPR3 ▸
TAS2R45 ▸ TAS2R19 ▸ RXFP4 ▸ TAS2R38 ▸ MTNR1B ▸ ADRA2B ▸ CCL19 ▸
GRM6 ▸ LPAR5 ▸ GALR1 ▸ S1PR2 ▸ CCR4 ▸ ADORA3 ▸ TAS2R39 ▸
XCR1 ▸ NPB ▸ CCR7 ▸ APLNR ▸ GNG2 ▸ GALR2 ▸ P2RY13 ▸
CCL16 ▸ CCR8 ▸ CCR10 ▸ KNG1 ▸ GNB1 ▸ GRM2 ▸ CCR6 ▸
GNAI2 ▸ PYY ▸ C5AR1 ▸ GALR3 ▸ CHRM2 ▸ GPER1 ▸ CCL27 ▸
MCHR2 ▸ TAS2R50 ▸ ANXA1 ▸ HTR1B ▸ TAS2R20 ▸ OPRD1 ▸ HTR1F ▸
INSL5 ▸ NPY2R ▸ CCR9 ▸ PPBP ▸ TAS2R16 ▸ TAS2R8 ▸ S1PR1 ▸
BDKRB2 ▸ S1PR4 ▸ TAS2R1 ▸ TAS2R43 ▸ HTR5A ▸ SUCNR1 ▸ GABBR2 ▸
TAS2R46 ▸ TAS2R3 ▸ GABBR1 ▸ CHRM4 ▸ PMCH ▸ GRM8 ▸ U2AF1 ▸
P2RY4 ▸ GNAT3 ▸ TAS2R30 ▸ S1PR5 ▸ HTR1D ▸ RXFP3 ▸ GRM7 ▸
NPY5R ▸ DRD3 ▸ TAS2R10 ▸ SSTR1 ▸ CCR1 ▸ ADORA1 ▸ NMUR1 ▸
TAS2R9 ▸ SSTR2 ▸ TAS2R4 ▸ TAS2R42 ▸ PENK ▸ DRD2 ▸ TAS2R13 ▸
FPR1 ▸ HCAR2 ▸ NPY1R ▸ TAS2R40 ▸ ADRA2A ▸ MTNR1A ▸ TAS2R14 ▸
PTGER3 ▸ PPY ▸ CCL25 ▸ HTR1A ▸ HCAR3 ▸ GRM3 ▸ BDKRB1 ▸
PTGDR2 ▸ TAS2R7 ▸ TAS2R60 ▸ OPRL1 ▸ CX3CR1 ▸ TAS2R31 ▸ TAS2R41 ▸
TAS2R5 ▸ NMU ▸ DARC ▸ GRM4 ▸ NMUR2 ▸ GNAI3 ▸ SSTR4 ▸
NPBWR1 ▸ PDYN ▸ PNOC ▸ DRD4 ▸ SSTR3 ▸ OPRK1 ▸ CCR2 ▸
ADRA2C ▸ MT-RNR2 ▸ P2RY12 ▸ C3AR1 ▸ OXER1 ▸ HTR1E ▸ SSTR5 ▸
Data information
Please see the Gene Interactions Track Manual.