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EGFR — PTPRF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: EGFR → PTPRF (decreases, PTPRF Activity, EGFR Activity) Kulas et al., J Biol Chem 1996*
  Evidence: Reduced LAR levels also resulted in increases of over 300% and 250% in epidermal growth factor (EGF)- and hepatocyte growth factor (HGF)-dependent receptor autophosphorylation, respectively, as well as a severalfold increase in substrate tyrosine phosphorylation.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 59 proteins (association, tandem affinity purification) Li et al., Molecular systems biology 2013