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FGF7 — MMP2
Text-mined interactions from Literome
Steinberg et al., Development 2005
:
FGF7 signaling
increases FGFR1b and FGF1 expression, and
MMP2 activity, when compared with FGF10, resulting in increased cell proliferation and expansion of the epithelial bud, whereas FGF10 stimulates localized proliferation at the tip of the duct ...
FGF7- and FGF10 mediated morphogenesis is
inhibited by an
MMP inhibitor and a neutralizing antibody to FGF1, suggesting that both FGF1 and MMPs are essential downstream mediators of epithelial morphogenesis
Uitto et al., Am J Pathol 1998
(Gingivitis...) :
In these cells,
MMP-13 expression at the mRNA and protein level was potently
enhanced ( up to sixfold ) by tumor necrosis factor-alpha, transforming growth factor-beta(1), and transforming growth factor-alpha and by
keratinocyte growth factor in the presence of heparin