Gene interactions and pathways from curated databases and text-mining

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FAS — PCNA

Text-mined interactions from Literome

Nath et al., Oncogene 2003 : Although Rb is inactivated by phosphorylation by cyclins D and E and their associated kinases during cell cycle progression, we find that Rb is inactivated upon apoptotic stimulation by Fas through the mediation of p38 kinase, independent of cyclins and cyclin dependent kinases (cdks)
Wu et al., World J Gastroenterol 2004 (Carcinoma...) : VES inhibited the growth of gastric cancer cells by inducing Fas expression and inhibiting PCNA expression
Bosque et al., J Leukoc Biol 2008 (Autoimmune Diseases...) : Our data indicate that in human CD8+ T-cell blasts, Fas ligation, and especially Apo2L/TRAIL induce the p53 dependent decrease in cyclin-B1 levels
Ma et al., Archives of medical science : AMS 2013 : Meanwhile, EsA reduced the serum IL-6 and TNF-a levels ( p < 0.05 ), inhibited the expression of PCNA and promoted the expression of caspase-3, Fas and FasL in animals of the treated group ( p < 0.05 )