Gene interactions and pathways from curated databases and text-mining

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IL3 — PTK7

Text-mined interactions from Literome

Torigoe et al., Blood 1992 (Leukemia, Myeloid, Acute...) : Interleukin-3 regulates the activity of the LYN protein-tyrosine kinase in myeloid committed leukemic cell lines ... Previous studies have shown that IL-3 induces rapid increases in protein-tyrosine kinase ( PTK ) activity in IL-3 -- dependent cells
Kanakura et al., Blood 1990 (Leukemia, Megakaryoblastic, Acute) : We have investigated the effects of GM-CSF and IL-3 on protein tyrosine-kinase activity in a human cell line, MO7E, which proliferates in response to either factor
Chen et al., Oncogene 1997 : No changes in Bax or Bcl-2 protein level were noted after IL-3 withdrawal and/or activation of v-Abl PTK
Tsubokawa et al., Eur J Biochem 1997 (Leukemia, Myeloid, Acute) : In the current study, we demonstrated that a non-receptor-type protein-tyrosine kinase , Syk, was immediately activated by the stimulation with IL-3 or granulocyte colony stimulating factor in AML193 cells