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SOAT1 — STAT3

Text-mined interactions from Literome

Rubin Grandis et al., Laryngoscope 2000 (Carcinoma, Squamous Cell...) : In these tumor cells in culture, EGFR stimulation initiates signaling via persistent activation of STAT proteins, particularly Stat3
Smithgall et al., Oncogene 2000 : Together these approaches provide strong evidence that Stat activation , particularly of Stat3 and Stat5, plays an important role in myeloid differentiation and survival
Suzuki et al., Exp Neurol 2001 (Brain Ischemia...) : JAK-STAT is the major downstream signal pathway of interleukin-6 (IL-6) cytokine family and is regulated by Tyr705 phosphorylation of Stat3
Vidal et al., Eur J Immunol 2001 : Furthermore, STAT1 activation but weak or no activation of STAT3 or STAT5 respectively, could be detected in MB-stimulated MDM. Using MonoMac6 cells, we observed high C/EBPbeta and AP-1 but weaker and transient NF-kappaB activation by MB.Moreover, the truncated form of C/EBPbeta, known to repress HIV-1 transcription, was detected in extracts from MB-treated THP-1 cells
Liu et al., Zhonghua Yi Xue Za Zhi 2001 : STAT1 and STAT3 antisense oligonucleotides inhibited both STAT DNA binding activity and TIMP1 mRNA expression in mesangial cells
Chen et al., Kidney Int 2002 : EMSA showed that STAT1 and STAT3 antisense oligonucleotides could inhibit both thrombin induced STAT-DNA binding activities and TIMP-1 mRNA expression ; the supershift assay showed that the SIF band consisted of STAT1 and STAT3 proteins
Guo et al., J Interferon Cytokine Res 2002 (Carcinoma, Hepatocellular...) : Stat activation by orthovanadate caused the accumulation of PY-Stat3 in the GRP58 containing plasma membrane fraction
Liu et al., Zhonghua Shao Shang Za Zhi 2005 : In addition, the cells were divided into normal control, LPS stimulation, JAK2 inhibition ( with AG490 treatment 2 hours before LPS stimulation ), STAT1 inhibition ( with fludarabine treatment 2 hours before LPS stimulation ) and STAT3 inhibition ( with rapamycin treatment 2 hours before LPS stimulation ) groups
Krejci et al., J Cell Sci 2008 : Moreover, addition of active STAT1 and STAT3 to the FGF signal, by means of cytokine treatment, SRC mediated STAT activation or expression of constitutively active STAT mutants does not sensitize RCS chondrocytes to FGF mediated growth arrest
Bender et al., Hepatology 2009 (Carcinoma, Hepatocellular...) : We find that IL-27 stimulates hepatoma cells and hepatocytes by inducing a sustained signal transducer and activator of transcription ( STAT ) 1 and STAT3 activation