Gene interactions and pathways from curated databases and text-mining

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RAC1 — TLR4

Text-mined interactions from Literome

Li et al., Acta Anaesthesiol Taiwan 2007 (Inflammation) : The p47phox- and Rac 1-dependent NADPH oxidase activation, ROS production, and MAPK signaling pathways play critical roles in endotoxin enhanced TLR4 expression and TLR4 mRNA stabilization in VSMCs
Wen et al., J Exp Med 2010 (Peritonitis...) : Plexin-A4 is required for TLR induced activation of the small guanosine triphosphate hydrolase ( GTPase ) Rac1 ( ras related C3 botulinum toxin substrate 1 )