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EIF2AK2 — PTPN11
Text-mined interactions from Literome
Li et al., Virology 2006
:
We demonstrated that the direct binding of the NS1A protein to the N-terminal 230 amino acid region of
PKR can serve as such a common mechanism and that this binding does not
require the RNA binding activity of the
NS1A protein ... The lack of
requirement for
NS1A RNA binding activity for the inhibition of
PKR activation in vivo was established by two approaches
Tan et al., J Interferon Cytokine Res 1998
:
Finally, the functional
role of
NS1 in
PKR inhibition was substantiated using an in vivo assay for PKR activity