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ITGA5 — MAPK7
Text-mined interactions from Literome
Qiang et al., Exp Hematol 2000
:
Activation of
mitogen activated protein kinase through
alpha5/beta1 integrin is required for cell cycle progression of B progenitor cell line, Reh, on human marrow stromal cells
Chen et al., Zhonghua Wai Ke Za Zhi 2006
(Prostatic Neoplasms) :
Using flow-cytometry, the
effects of EGF and the
mitogen activated protein kinase ( MAPK ) signal pathway inhibitor PD98059 on the expression of
integrin alpha5 and beta1 subunits on DU145 cell surface were analyzed
Camacho-Leal et al., J Cell Physiol 2007
(MAP Kinase Signaling System) :
Inhibition of PI3-K and ILK, but not
MAPK ,
prevented the
alpha5beta1 integrin activation
Pandolfi et al., J Cell Physiol 2007
(Kidney Failure, Chronic...) :
Interestingly, ESRD-RBC induced increased expression of adhesion molecules was
prevented by Annexin-V ( AnV, able to mask PS on RBC surface ),
anti-integrin-alpha(v)beta3 , anti-thrombospondin-1 (TSP-1), and PD98059 ( a selective inhibitor of
MAPK phosphorylation )
Reyes-Reyes et al., Exp Cell Res 2008
(Adenocarcinoma...) :
We have previously shown that P-selectin binding to Colo-320 human colon carcinoma cells induces specific activation of the
alpha(5)beta(1) integrin with a concomitant increase of cell adhesion and spreading on fibronectin substrates in a phosphatidylinositol 3-kinase (PI3-K) and p38
MAPK dependent manner