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PSMG1 — TP53
Text-mined interactions from Literome
Ciani et al., Brain Res Mol Brain Res 1999
(Brain Ischemia) :
Induction of the
PAC1-R ( PACAP-type I receptor ) gene by
p53 and Zac ... We report here that
p53 and Zac
induce expression of the
PAC1-R gene
Yin et al., Nature 2003
:
Here we show that during apoptosis,
p53 activates transcription of
PAC1 by binding to a palindromic site in the PAC1 promoter ... We conclude that, under specific stress conditions,
p53 regulates transcription of
PAC1 through a new p53 binding site, and that PAC1 is necessary and sufficient for p53 mediated apoptosis