Stove et al., Oncogene 2004
(Melanoma) :
Secretion of follistatin , either native or after retroviral transduction, efficiently prevented Smad activation or activation of an activin-responsive luciferase reporter construct
Coutts et al., Dev Biol 2008
:
Activin A increased and follistatin decreased phosphorylation of SMAD2/3 in vitro, and activin increased SMAD2 and decreased KITLG mRNA expression