Gene interactions and pathways from curated databases and text-mining

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CES1 — IRF6

Text-mined interactions from Literome

Kojima et al., Oncogene 2000 (Adenocarcinoma...) : Positive correlations were found between PGE2 production and activation of nuclear factor (NF)-kappa B as well as expression of both COX-2 mRNA and protein in LPS stimulated CE-1 cells
Figueiredo et al., Vet Immunol Immunopathol 2008 : There was a four-fold increase in PCA when monocytes were incubated with LPS in the presence of CES , HI-CES or AES compared to LPS without serum
Holen et al., Fish Shellfish Immunol 2012 : LPS cell activation increased mRNA expression of interleukin 8 ; interleukin-1ß ; cyclooxygenase 2 ; leukocyte derived chemotaxin 2 ; carboxyl-esterase 2 and environmental biomarker cytochrome P450 1A